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Right, that's what I figured. Cos as soon as the fight with the Brothers was done, I got a cutscene showing me loading the sarcophagus into a truck... and then instant teleport over to LaCroix's penthouse hall place. He stands by the window and I can go talk to him (which completes a quest or two ...

I got this patch from GS:

Vampire: The Masquerade - Bloodlines True VTMB v5.04AT Unofficial Patch
Posted Oct 1, 2007 | From: Tessera | Size: 53.6MB

My system very comfortably overshoots the game's requirements, so no problem there.

I'll try reloading before the brothers Mangle and Maim (sorry ...

This is my first run through this game. Good stuff, good fun, good game.

But...

I've been getting on with the main quests after polishing off everything else and now I've just recovered the Sarcophagus and gotten automagically teleported back to LaCroix's tower. Cool. Let's crack that baby open ...