The only one (CRPG) I know of "specifically" is NWN, but I suspect KOTOR has the capability built into it as well. A couple of others I know about are Strategy types, such as Starcraft, Warcraft. I don't include shooters in what I hope to see as a nice group of games with some variety to them that will play for 2-3 people in an ordinary house's game room (not talking a LAN Party for dozens in rented space).
Somewhere, I read that it's best to uninstall the expansions and play only the basic NWN module -- the expansions being less stable?