This forum is to be used for all discussions pertaining to BioWare's Neverwinter Nights, its Shadows of Undrentide and Hordes of the Underdark expansion packs, and any user-created or premium modules.
Gargoyle Skulls are for crafting armor - I believe one of the combinations is a +1 leather armor with the skull, but the end product is a medium weight armor, so have to plan accordingly before making it.
The empty bottles can be used to make potions at the Alchemist Lab in Quint's Tower in Castle Jhareg. I don't know if the same can be done at other alchemist tables elsewhere in the lands but the recipe given was a healer's kit and an empty bottle placed in the table, then cast the spell on the table. If you're not a caster you're more than likely going to fail - even if you can read the spell off the scroll.