um, well it's really a matter of taste and strategy I suppose. Here's my theory on it:
The first character I tried was a Scout, a class with long blade in Major skills. What I found was that because of all the random fighting you get into, my long blade skill grew very quickly. I couldn't practice other skills quickly enough to keep up with long blade, and the character went up levels very quickly, hacking away but not growing in other ways. At level up I would rarely get very good bonuses except for Strength.
For my current character, who has now gone much farther in the game than that first one, I did sort of what you describe in your post - I put my primary weapons and armor in miscellaneous skills, and I put skills that I felt did not progress quickly enough for me, like Speechcraft, Mercantile, Enchanting, Security and especially Marksman - in major skills, the idea being that although the fighting skills and athletics and acrobatics would advance quickly from their early low numbers, they would not dictate leveling, but instead the progress in these other skills would determine level, and the character would not be either stuck training up skills or solving every problem with a sword.
I personally have liked the way it worked out a lot, and I have in general gotten 5x bonuses in 3 attributes each level up, which was a goal. There are some tweaks I would do to it though - one being Sneak. I had such an easy time sneaking with the Scout that I thought Sneak was an easy skill to advance, but with it in Miscellaneous it has been very hard to advance, i wish I had put it in major or minor.
Now, Fable is probably going to tell you not to worry about it too much, and he is right in a way.

May you walk on warrrrm sannd....