on my 2nd time through the game. First time thru I played a couple of multi-classed half-elves along with the usual NPCs and was disgusted with their lack of HP . They barely broke 80 by the end of the game, hitting the XP cap. Interestingly, the Jaheira romance completed fine in this game even though I never bought her the locket. I'm thinking holding onto the lock of her hair from the Ployer quest works just as well. Terminsel showed up in a random encounter area after I was "waylaid by enemies" in Ch 6.
This time I'm playing dual classed humans (Ftr/Thief) and (Cleric/Mage) plus an Archer (great class with all the great leather armor in this game) with Anomen and Minsc as permanent party members and a final slot that rotates according to the quest but generally has Nalia in it. Gives me equivalent of 3 heavy fighters, 2 mages, 2 clerics, a thief and the archer. Plus the Archer and Minsc get their Druid spells (for what that's worth, since they never get Insect Plague). I've decided I really like dualling into Thief classes because they level up so quickly. I regained my fighter skills with fewer thief XP than it took to originally gain them.
Odd things I've tried this game:
1) Kicked Immie out of the party to add Yoshimo. Since I had 3 player chars, Imoen, Jaheira and Minsc, it was her or Jaheira. She still goes through the scene in Waukeen's promenade after you get out of Irenicus' digs, so no plot effects so far.
2) Looking for a buyer or practical use for a couple of spare demon hearts I picked up during the planar sphere quests. They seem to resist decay pretty well
Currently wandering around Brynnlaw, trying to find a way into Galvena's place without having to get Sanik killed off. Looks like it's a plot point, though.