The latest video interview from GameInformer on The Witcher 3: Wild Hunt covers monster hunting. Apparently monster hunting will be divided between quest-based and more generic notice board style monster hunts, which will still involve some investigation of clues and require the same kind of preparation that the developers introduced in The Witcher 2 but with some added fighting bonuses related to monster knowledge which they're calling "focus mode". On top of all of this, crafting materials and special mutagens will also be available solely if the player engages in monster hunting.